10 Best Clinical Research Organizations In The USA

With the growing population, diseases affecting mankind are also increasing. The old medications are being obsolete for certain diseases like bacterial infections, and new effective medicines are urgently needed. The clinical research institutions facilitate drug manufacture by running preclinical and clinical tests on the drugs. In addition, they also study safety, efficacy, and effectiveness of medical devices, diagnostic products, and treatment regimens intended for human health. The healthcare industry is booming with a lot of clinical research institutions in the US and all around the world.

Top 10 American CROs

Top 10 American CROs

The United States of America has some of the top clinical research organizations in the world. Amongst them, here is the list of the 10 Best Clinical Research Organizations In The USA.

1. Covance

Annual Revenue: $9.6B
Headquarters: Princeton, New Jersey
Number of Employees: 50,000+
Total Funding: $0
Status: Public, Subsidiary of LabCorp
Founded: 1996

In 2014, LabCorp acquired Covance for $6.1B. Covance, a global contract research organization under LabCorp, is the world’s leading healthcare diagnostics company, providing comprehensive clinical laboratory services and end-to-end solutions for drug and diagnostics development and commercialization. With its mission to bring new and innovative medicines to patients sooner, it has worked on more than 50 drugs available in the market today. It provides drug development services across all phases of development and multiple therapeutic areas.


Annual Revenue: $9.74B
Headquarters: Durham, North Carolina
Number of Employees: 55,000
Operating Income: $1.33B
Status: Public, Independent Company
Founded: 1982

Working to enhance healthcare by integrating health information technologies and clinical research, IQVIA explores a new path to better health outcomes via Human Data Science. It integrates the study of human science with breakthroughs in data science and technology to advance our understanding of human health, and help everyone make better, more insightful decisions.

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3. Syneos Health

Annual Revenue: $1.9B
Headquarters: Morrisville, North Carolina
Number of Employees: 21,000
Total Funding: $0
Status: Public, Independent Company
Founded: 1999

Syneos Health integrates all the disciplines involved in bringing new therapies to market, from clinical to commercial, for biopharmaceutical solutions. In January 2018, INC Research merged with inVentiv Health, the parent company of a subsidiary called Syneos, and the resulting company was named Syneos Health.

4. Parexel International

Annual Revenue: $2.4B
Headquarters: Waltham, Massachusetts
Number of Employees: 18,660
Total Funding: $0
Status: Public, Subsidiary of Pamplona Capital Management LLP
Founded: 1982

Parexel International is involved in advancing the success of biopharmaceutical and medical device industries for the development and commercialization of new medical therapies worldwide. It is the second-largest clinical research organization in the world and has helped develop approximately 95% of the 200 top-selling biopharmaceuticals on the market today.

5. PRA Health Sciences

Annual Revenue: $2.7B
Headquarters: Raleigh, North Carolina
Number of Employees: 16,400
Total Funding: $305.6M
Status: Public, Subsidiary of Kohlberg Kravis Roberts & Co. L. P
Founded: 1976

PRA participated in the pivotal or supportive trials and/or key NDA support services that led to the approval of 85 important products currently on the market. Its aim is to improve the drug development process for getting better medicines to market sooner.

6. Pharmaceutical Product Development

Annual Revenue: $1.9B
Headquarters: Wilmington, North Carolina
Number of Employees: 18,583
Total Funding: $0
Status: Private, Independent Company
Founded: 1985

PPD applies innovative technologies, therapeutic expertise, and a firm commitment to provide comprehensive, integrated drug development, laboratory, and lifecycle management services. Its clients and partners include pharmaceutical, biotechnology, medical device, academic, and government organizations. It helps to bend the cost and time curve of drug development and optimize value in delivering life-changing therapies to improve health.

7. Charles River Laboratories

Annual Revenue: $2.27B
Headquarters: Wilmington, Massachusetts
Number of Employees: 14,700
Total Funding: $224M
Status: Public, Independent Company
Founded: 1947

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Having worked on about 85% of the drugs approved by the FDA in 2018, Charles River  Laboratories operates 80+ facilities in 20 countries worldwide. It offers a wide range of products and services that span the entire drug discovery and development continuum and can be tailored to specific research conditions.

8. Icon

Annual Revenue: $2.2B
Headquarters: Leopardstown, County Dublin
Number of Employees: 13,250
Total Funding: $0
Status: Public, Independent Company
Founded: 1990

Icon helps its clients to accelerate the development of drugs and devices that save lives and improve quality of life. It offers a full range of consulting, development, and commercialization services from a global network of offices in 37 countries.

9. WuXi AppTec

Annual Revenue: $674.3M
Headquarters: Shanghai, Shanghai Municipality
Number of Employees: 3,800
Total Funding: $2.6B
Status: Public, Subsidiary of WuXi PharmaTech, Inc, Shanghai Stock Exchange
Founded: 2000

WuXi AppTec Group, with 18 facilities in the USA and China combined, is a global pharmaceutical, biopharmaceutical, and medical device company. It covers the development cycle through five core operations, including small molecule R&D and manufacturing, biologics R&D and manufacturing, cell therapy and gene therapy R&D and manufacturing, medical device testing, and molecular testing and genomics.

10. Medpace Holdings

Annual Revenue: $704.6M
Headquarters: Cincinnati, Ohio
Number of Employees: 2,900
Total Funding: $161M
Status: Public, Subsidiary of Cinven Limited
Founded: 1992

Medpace provides services for Phase I-IV of drug and medical device development services, including regulatory services and central laboratory services. It combines scientific guidance, efficient clinical trial management, global regulatory leadership, and innovative technologies to deliver high-quality results.

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